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分析动态对比增强超声波和细胞癌的血管生成活性之间的相关性

Xiuyun Lu¹, Jianqing Ye², Xiuwu Pan²

¹Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.

Ultrasound international open

|September 22, 2025

概括

动态对比增强超声波 (DCE-US) 可以预测细胞癌 (RCC) 中的血管生成活性. 这种成像技术显示出非侵入性评估瘤特征的潜力.

科学领域:

医疗成像医学成像
在瘤学瘤学.
放射学放射学是一门学科.

背景情况:

细胞癌 (RCC) 是一种常见的恶性瘤.
评估RCC中的血管生成活性对于治疗计划至关重要.
目前评估血管生成的方法可能是侵入性的.

研究的目的:

调查动态对比增强超声波 (DCE-US) 与细胞癌 (RCC) 中血管生成活性之间的相关性.

主要方法:

在手术前,五十名经过基因病理学证明的RCC病变的患者接受了B模式超声波 (BMUS) 和对比增强超声波 (CEUS).
使用VueBox软件对CEUS数据进行了定量分析.
根据基因病理学和免疫组织化学结果,患者被分为活跃和不活跃的血管生成组.

主要成果:

有活性血管生成的RCC在CEUS皮质阶段 (72.6%,P=0.027) 显示过度增强.
与不活跃组相比,活跃血管生成组的时间强度曲线 (TIC) 显示出更快,更大的增强和曲线下的面积增加.
在活性血管生成组 (P<0.05) 中观察到更高的洗进率和洗进输液指数.

结论:

DCE-US分析表明,在预测RCC病变中的血管生成活性方面具有潜在价值.
在RCC中,CEUS定量参数和TIC可以区分活性和非活性血管生成.

关键词:

手术手术手术手术手术手术手术瘤是一个瘤.超声波超声波是指超声波的使用.尿道尿道尿道尿道

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