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成年人夜间饮食综合征的药理和社会心理干预措施
Lucas Ribeiro Dos Santos1,2, Márcio Luís Duarte2, Virgínia Fernandes Moça Trevisani1
1Department of Evidence-Based Healthcare, Federal University of Sao Paulo, Cochrane Center of Brazil, Sao Paulo, Brazil.
Frontiers in psychiatry
|September 22, 2025
概括
这次审查发现,药物治疗和治疗都可能有助于治疗夜间饮食综合征 (NES). 塞特拉林在减轻症状方面表现有希望,而放松技巧改善了饮食行为,尽管需要更多的研究.
科学领域:
- 行为科学 行为科学
- 临床心理学 临床心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 病态的饮食模式是复杂的,受心理,生物和环境因素的影响.
- 夜间饮食综合征 (NES) 涉及过度的夜间食物消费,通常与昼夜节律障碍和心理社会问题有关.
- NES经常与常规减肥尝试失败有关,特别是在肥胖的人群中.
研究的目的:
- 评估药理学和心理社会干预措施对成人夜间饮食综合征 (NES) 的有效性.
- 评估症状改善 (减少夜间进食/醒来) 和减肥作为主要结局.
- 检查二次结果,包括生活质量,并发病,睡眠和功能.
主要方法:
- 随机对照试验 (RCT) 的系统审查,将干预措施与对照组进行比较.
- 在多个数据库中进行搜索,包括CENTRAL,MEDLINE,EMBASE和Psych INFO.
- 包括5个RCT,由于干预异质性,结果以叙事形式呈现.
主要成果:
- 药理学试验 (塞特拉林,埃斯基塔洛普拉姆,阿戈梅拉丁) 的结果各不相同;塞特拉林显示最显著的NES症状改善.
- 心理社会干预措施,如渐进性肌肉放松,在减少晚上的饮食和改善早上的饥饿方面表现出好处.
- 减肥结果是可变的,一些试验报告了干预组中适度减肥.
结论:
- 药理学和心理社会方法都显示出治疗NES的潜力.
- 塞特拉林可以减轻症状并提高生活质量;渐进的肌肉放松可以改变饮食行为.
- 有限的研究和异质性需要进一步的研究,以获得最佳的NES治疗策略,对当前的证据进行低等级的建议.
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