对于MASLD的数字行为改变干预措施的有效性和活性成分:系统审查和元分析
Hollie Smith1, Rebecca Livingston2, Kirsten Ashley1
1School of Health and Life Sciences, Teesside University, Middlesbrough, UK.
JHEP reports : innovation in hepatology
|September 22, 2025
概括
对代谢功能障碍相关的脂肪性肝病 (MASLD) 的数字干预没有改善体重或肝脏健康. 然而,应用程序交付和自我监控等特定功能对未来的MASLD管理策略显示出希望.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 数字健康数字健康
- 行为科学 行为科学
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 是一个全球性的健康问题.
- 改变生活方式对于管理MASLD至关重要.
- 数字行为改变干预提供了一个可扩展的方法来促进生活方式的改变.
研究的目的:
- 系统地审查数字行为改变干预措施对MASLD的有效性.
- 确定能改善MASLD患者体重和肝脏相关结果的活性成分.
主要方法:
- 在2025年1月之前对五个数据库进行系统审查.
- 对11项涉及1288名参与者的研究进行了元分析和叙事综合.
- 承诺分析以确定有效干预特征.
主要成果:
- 数字干预并没有显著降低重量 (大规模杀伤性武器-2.07公斤).
- 肝酶 (ALT,AST) 没有显著改善.
- 有效的特点包括基于应用程序的交付,≥6个月的持续时间,自我监测,反和社会支持.
结论:
- 目前的数字干预措施在改善MASLD患者的体重和肝脏结果方面并不有效.
- 整合特定功能,如自我监控和社会支持,可能会提高效率.
- 未来的研究应该确定从这些干预中获益最多的个人.
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