对EAT厚度与心力衰竭患者的预后之间的相关性进行分析,其中保留了喷射分数
Jianfei Ma1, Hongbin Zhang1, Ting Ma2
1The Third Department of Cardiovascular, Cangzhou Central Hospital, Cangzhou, Hebei, China.
Frontiers in cardiovascular medicine
|September 22, 2025
概括
副心脏脂肪组织 (EAT) 厚度是心脏衰竭预后不佳的重要预测因素,其中包括保留喷射分数 (HFpEF). 增加EAT厚度表明结果更差,并反映了左心室重塑.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 医疗成像医学成像
背景情况:
- 保持喷射分数 (HFpEF) 的心力衰竭是一个重大的临床挑战.
- 确定HFpEF可靠的预后标志物对于患者管理至关重要.
- 心脂肪组织 (EAT) 已成为影响心脏功能的潜在因素.
研究的目的:
- 研究心表脂肪组织 (EAT) 厚度与HFpEF患者的预后之间的相关性.
- 为了确定EAT厚度是否可以作为HFpEF患者的非侵入性预后指标.
主要方法:
- 研究了一组156名HFpEF患者和150名健康对照.
- 患者被跟踪1年,以评估预后,将他们分为好和坏的结果组.
- 测量了EAT厚度,左心室质量指数 (LVMI),左心室直径 (LAD) 和左心室末端透气直径 (LVEDD).
主要成果:
- 与对照组相比,HFpEF患者的EAT厚度,LVMI,LAD和LVEDD增加,LVEF较低.
- EAT厚度与LVEF负相关,与LVMI,LAD和LVEDD正相关.
- 在预后不佳的组中观察到更高的EAT厚度,血乳酸和血清肌氨酸,而血红蛋白和估计的球粒则较低.
结论:
- EAT厚度与HFpEF严重程度相反,反映了左心室重塑.
- 降低的血红蛋白,增加的EAT厚度和升高的血乳酸被确定为HFpEF中预后不佳的危险因素.
- EAT厚度显示出作为HFpEF中不良结果的有价值的非侵入性预后指标的潜力.
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