老年人营养风险指数作为通过皮肤进行冠状动脉干预的老年患者结果的预测指标:更新的系统性审查和元分析

Fei Fang¹, Xiaowang Li²

¹Fei Fang Department of Geriatrics, Huzhou Third Municipal Hospital, The Affiliated Hospital of Huzhou University, Huzhou, Zhejiang Province 313000, P.R. China.

Pakistan journal of medical sciences

|September 22, 2025

概括

低老年营养风险指数 (GNRI) 评分与接受皮肤冠状动脉干预 (PCI) 的老年患者的死亡风险和主要心血管不良事件的风险更高有关. 营养评估对于改善这一群体的结果至关重要.

科学领域:

心脏病学心脏病学
老年病的医生老年病的医生
营养科学营养科学

背景情况:

老年患者的营养状况至关重要,特别是那些接受入侵性心脏手术的患者.
老年营养风险指数 (GNRI) 是评估老年人营养风险的有效工具.
穿皮冠状动脉干预 (PCI) 是一种常见的治疗老年人冠状动脉疾病的程序.

研究的目的:

评估老年营养风险指数 (GNRI) 与接受皮肤冠状动脉干预 (PCI) 的老年患者的临床结果之间的关联.
综合GNRI观测研究的证据和诸如全因死亡率 (ACM),主要心血管不良事件 (MACE) 和对比诱导的急性损伤 (CI-AKI) 等结果.

主要方法:

在主要数据库 (PubMed,科学网,Scopus,Embase) 进行了系统的文献搜索,截至2024年4月30日.
包括观察性研究报告ACM,MACE和CI-AKI的调整效果大小.
使用随机效应模型进行了元分析,并进行了子组分析和出版偏差评估.

主要成果:

分析了24项涉及35,002名参与者的研究.
低GNRI得分与所有原因死亡率 (HR 2.50) 和主要心血管不良事件 (HR 2.18) 的风险增加有显著关联.
在GNRI得分较低的患者中,观察到对比引起的急性损伤 (HR 1.87) 的风险较高.

结论:

低GNRI得分始终预测老年PCI患者的ACM,MACE和CI-AKI风险增加.
这些发现强调了营养评估和干预的重要性,以优化这一脆弱患者群体的结果.
检测到ACM和MACE的出版偏差,需要谨慎解释结果.

关键词:

冠状动脉疾病是一种冠状动脉疾病.死亡率死亡率死亡率心肌梗塞的心脏病发作营养状态营养状况通过皮肤进行冠状动脉干预.

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