在血液性恶性瘤的III期临床试验中报告和表示种族和民族数据
Tianyi Wang1, Ambily Banerjee2, Dina Gifkins1
1Johnson & Johnson, Raritan, NJ, USA.
Future science OA
|September 22, 2025
概括
种族和民族少数群体的临床试验参与率仍然很低,特别是在非霍奇金淋巴瘤 (NHL),白血病和多发性髓瘤 (MM) 等血液癌症中. 需要新的策略来改善患者在研究中的多样性.
科学领域:
- 在瘤学瘤学.
- 临床试验 临床试验
- 健康差异 在健康上的差异
背景情况:
- 种族和少数民族在临床试验中的代表性不足是一个持续的问题.
- 在研究中确保多样化的患者群体对于可概括的结果至关重要.
研究的目的:
- 评估非霍奇金淋巴瘤 (NHL),白血病和多发性骨髓瘤 (MM) 的第三期临床试验中种族和民族群体的代表性.
- 将试验参与者的人口统计数据与来自监测,流行病学和最终结果 (SEER) 数据库的人口数据进行比较.
主要方法:
- 在clinicaltrials.gov数据库中确定了NHL,白血病和MM的III期临床试验.
- 分析了参与者的种族和种族数据,并与SEER人口数据进行了比较.
主要成果:
- 分析包括来自119项试验的53 821名参与者.
- 白人参与者占多数 (77.3%).
- 与SEER数据相比,亚洲/太平洋岛民,西班牙裔/拉丁裔,黑人/非洲裔美国人和美国印第安人/阿拉斯加土著人的代表性在试验中较低.
结论:
- 尽管有努力,但非白人人口在临床试验中的代表性仍然不足.
- 需要创新策略和现实数据来改善患者多样性,并设定招聘目标.
关键词:
临床试验临床试验是指临床试验的临床试验.在 SEER 计划中,民族身份 民族身份在白血病中,白血病.多发性骨髓瘤是多发性骨髓瘤的一种疾病.非霍奇金淋巴瘤的非霍奇金淋巴瘤.种族 种族 种族 种族更多相关视频
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