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Updated: Aug 12, 2026

Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray
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Demonstrating a Multi-drug Resistant Mycobacterium tuberculosis Amplification Microarray

Published on: April 25, 2014

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利用保存的G-四重复合体进行光检测Mycobacterium结核病

Vasudhar Bhat S V1, Sumon Pratihar1, Krithi K Bhagavath1

  • 1Bioorganic Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur P.O., Bengaluru, 560064 Karnataka, India. tgraju@jncasr.ac.in.

Chemical communications (Cambridge, England)
|September 22, 2025
PubMed
概括

我们在Mycobacterium tuberculosis (MTB) 中检测到一种特定的DNA结构,G-四重复 (GQ). 这种G-quadruplex可靠的形态多态 (GQ-RCP) 方法可以在诊断试验中准确检测MTB.

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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

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相关概念视频

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...