低血动力学特征与非常低出生体重婴儿的急性损伤有关
Omer Guran1, Funda Yavanoglu Atay1, Ozlem Sahin1
1Department of Neonatology, University of Health Sciences, Umraniye Training and Research Hospital, Umraniye, Istanbul, Turkey.
Pediatrics international : official journal of the Japan Pediatric Society
|September 22, 2025
概括
急性损伤 (AKI) 影响了16%的非常低出生体重 (VLBW) 婴儿. 低血压和长期使用内类药物是关键的危险因素,需要在高风险新生儿中早期识别和血液动力学监测.
科学领域:
- 新生儿科学 新生儿科学
- 儿科脏病学 儿科脏病学
- 关键护理医学 关键护理医学
背景情况:
- 患有急性损伤 (AKI) 的非常低出生体重 (VLBW) 婴儿可能面临长期慢性病风险.
- 有限的大型队列研究存在于VLBW婴儿的AKI风险因素.
研究的目的:
- 为了追溯识别VLBW婴儿AKI发展的风险因素.
- 为了比较具有和没有AKI的VLBW婴儿的临床特征.
主要方法:
- 在2019-2022年期间入院新生儿重症监护室的VLBW婴儿 (<1500g) 的回顾性分析.
- 对那些患有AKI的婴儿与没有AKI的婴儿进行比较.
主要成果:
- 在VLBW婴儿中,16% (35/218) 患有AKI.
- 较低的妊娠年龄,出生体重,更长的机械通风,因诺托普/万科米辛使用,PDA,NEC和IVH与AKI有关.
- 独立预测AKI的预测因素包括较低的妊娠年龄和≥3天的异能剂使用.
结论:
- 低血压是VLBW婴儿AKI的重要预测因素.
- 早期识别和密切的血液动力学监测对于预防早产新生儿的AKI至关重要.
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