维生素D水平与长期COVID的体征和症状之间的关联
Karn Matangkha1, Vichit Punyahotara1, Jarasphol Rintra1
1Department of Anti-Aging and Regenerative Medicine, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok 10110, Thailand.
Medical sciences (Basel, Switzerland)
|September 22, 2025
概括
低维生素D水平与患长期COVID症状的风险更高有关. 通过补充剂和阳光照射维持足够的维生素D可能有助于减少COVID-19患者的长期COVID流行和严重程度.
科学领域:
- 免疫学 免疫学 免疫学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 长期COVID,以COVID-19感染后的持续症状为特征,会影响多个器官.
- 维生素D在免疫功能中起着至关重要的作用,可能会影响长期COVID的发展.
研究的目的:
- 调查维生素D水平与COVID-19患者长期COVID迹象和症状的患病率之间的联系.
主要方法:
- 招募了170名患有轻度症状的成年COVID-19患者.
- 在诊断后60天内测量了血清25(OH) D水平,并对患者进行了至少3个月的随访.
- 数据包括人口统计,维生素D水平和自我报告的长期COVID症状.
主要成果:
- 64.7%的患者患有长期COVID,呼吸道,皮肤和一般症状是最常见的.
- 长期COVID患者的维生素D水平显著降低 (21.52 ng/mL与25.46 ng/mL).
- 维生素D缺乏与整体长期COVID (Adj. OR,5.80) 和增加的全身症状 (Adj. 内部利率,3.30). 这是一个很好的例子.
结论:
- 对COVID-19患者来说,评估和维持维生素D水平至关重要.
- 维生素D补充剂和阳光照射可能会降低长期COVID的风险和严重程度.
- 准维生素D状态可能是缓解长期COVID并发症的策略.
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