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冈比亚老年人骨质疏松症和肉症患病率的农村和城市差异:试点研究
Mícheál Ó Breasail1, Ayse Zengin1, Camille Pearse2
1Department of Medicine, School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash Medical Centre, Monash University, Clayton, VIC, Australia.
骨质疏松症和肉症在老年冈比亚人中很常见,农村和城市之间的差异因性别而异. 城市男性患骨质疏松症的风险更高,而农村参与者患低骨矿物质密度和肉症的比例更高.
科学领域:
- 老年学是一门学科.
- 骨健康 骨健康 骨健康
- 公共卫生 公共卫生
背景情况:
- 骨矿物密度 (BMD) 的农村和城市差异在高收入国家确立,但非洲快速城市化的地区的数据有限.
- 了解非洲人口老龄化中的骨和肌肉健康差异至关重要,因为寿命和城市化日益增加.
研究的目的:
- 为了比较居住在冈比亚农村和城市的老年人之间的骨和肌肉健康指标.
- 确定这些人群中骨质疏松症和肉症的患病率,并确定农村和城市之间的差异.
主要方法:
- 双能X射线吸收仪 (DXA) 和外围定量计算断层扫描 (pQCT) 用于评估骨矿物质密度 (BMD),骨矿物质含量 (BMC),骨面积 (BA) 和体积 BMD (vBMD).
- 骨质疏松症和肉症的患病率是使用既定标准 (NHANES III,EWGSOP2) 计算出来的.
- 进行了对年龄和脂肪质量指数 (FMI) 进行调整的线性回归分析,以比较农村和城市的结果.
主要成果:
- 骨质疏松症在城市男性和农村女性中更为普遍. 腰椎骨质疏松症和肉症在两性农村参与者中更为常见.
- 经过年龄和FMI调整后,城市的冈比亚人显示下部 (FN) 和全部 (TH) BMC,但骨面积更大 (BA).
- 城市男性有下皮皮层vBMD,而城市女性则表现出更大的辐射骨强度.
结论:
- 骨质疏松症和肉症在加比亚老年人中非常普遍,性别特异的农村-城市差异.
- 研究结果强调需要有针对性的公共卫生战略,以解决非洲老龄化人口的骨和肌肉健康问题,这些人口正在经历营养和流行病学的转变.
- 进一步的大规模人口研究对于有效的预防和干预计划至关重要.
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