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在焦点[¹⁸F]FDG-PET/CT甲状腺偶发性瘤中发现恶性瘤的五个美国风险分层系统的诊断性能

Chae Young Shin¹, Hye Shin Ahn², Dong Gyu Na³

¹Department of Radiology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Republic of Korea.

European radiology

|September 22, 2025

概括

超声波风险分层系统 (US-RSS) 有助于评估焦点[18F]氧葡萄糖 (FDG) -PET/CT甲状腺意外瘤 (TI) 中的恶性瘤风险. 虽然减少了活检,但一些系统对侵袭性癌症的敏感性较低,这表明可能需要调整活检标准.

科学领域:

核医学就是核医学.
放射学放射学是一门学科.
内分泌学在内分泌学.

背景情况:

焦点[18F]氧葡萄糖 (FDG) -PET/CT甲状腺意外瘤 (TI) 需要对恶性瘤进行准确的风险评估.
已建立的超声波风险分层系统 (US-RSS) 在评估TI时具有不同的诊断性能.

研究的目的:

评估由五个US-RSSs分类的结核恶性瘤 (ROM) 的风险.
评估US-RSS的诊断性能,使用活检标准来诊断焦点FDG-PET/CTTI中的恶性瘤.

主要方法:

对216名患者进行了回顾性队列研究,其中236名患者患有FDG-PET/CT TIs.
通过活检标准评估了五个美国RSS的诊断性能.
通过US-RSSs和SUVmax-US-RSS结合的标准分析了结的ROM.

主要成果:

在所有RSS中,中等风险的TI显示出高于预期的ROM (33.8-48.2%).
只有在中国TIRADS (35.0%) 中,低风险的TI具有显著更高的ROM (>20%).
美国甲状腺协会系统和韩国TIRADS对整体和侵略性恶性瘤具有最高的敏感性 (97.3%);ACR-TIRADS具有最高的特异性 (50.0%) 和最低的不必要活检率 (30.2%).

结论:

中等风险的TI在整个系统中增加了ROM;低风险的TI在C-TIRADS中增加了ROM.
美国RSS减少了不必要的活检,但欧洲TIRADS,ACR-TIRADS和C-TIRADS对攻击性恶性瘤的敏感性较低.
在欧洲和ACR-TIRADS中,中等风险结节和C-TIRADS中低风险结节可能需要较低的活检切断值.

关键词:

诊断诊断诊断诊断是一个偶尔发生的oma.阳位子辐射断层扫描-计算机断层扫描.甲状腺是什么?甲状腺是什么?超声波学超声波学超声波学

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