艾滋病毒感染男性的阴道和性功能:来自单中心研究的见解
Ilaria Bonaventura1, Valeria Hasenmajer1, Nicolò F D'Addario1
1Department of Experimental Medicine, Sapienza University of Rome, Viale del Policlinico 155, Rome, 00161, Italy.
Journal of endocrinological investigation
|September 22, 2025
概括
勃起功能障碍 (ED) 影响了70%的艾滋病毒感染者 (MLWH),其中有18.3%的男性患有阴道腺缺陷症. 像HAART这样的HIV治疗也会影响性功能,需要多学科的护理方法.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 性医学性医学性医学性医学
背景情况:
- 携带艾滋病毒的男性 (MLWH) 面临着独特的健康挑战.
- 低雄性和勃起功能障碍 (ED) 是MLWH的潜在并发症.
研究的目的:
- 估计MLWH中阴性腺和ED的流行率.
- 探索与艾滋病毒相关的变量和淋巴腺/性功能之间的关联.
主要方法:
- 激素评估和IIEF-15问卷评估了MLWH中的淋巴腺和性功能.
- 评估了人体测量和与艾滋病毒相关的参数,包括高活性抗逆转录病毒疗法 (HAART).
主要成果:
- 70%的MLWH经历了ED,而18.3%的人患有阴道腺缺陷症.
- 阴阴腺MLWH的BMI和吸烟率较高,17β-雌激醇的水平较低.
- 在使用整合酶链转移抑制剂时,ED更为普遍; 蛋白酶抑制剂的使用与较高的和雌激醇水平相关.
结论:
- 勃起障碍在MLWH中非常普遍和多因素.
- 降低丸激素和增加内脏脂肪有助于ED,但HIV因素如HAART也起作用.
- 最佳的护理需要一个多学科的方法,整合传染病和性医学专业知识.
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