在人类和动物莱什曼病中绘制非传统的莱什曼病:关于病原体多样性,地理分布和知识差距的范围审查协议
Denis Sereno1,2, Tahar Kernif3, Renato Leon4
1UMR177 Intertryp, Institut de Recherche pour le Développement, CIRAD, University of Montpellier, Montpellier, France.
PloS one
|September 22, 2025
概括
本综述绘制了人类和动物中新兴和非传统的莱什曼尼亚感染的地图,突出了诊断和监测的挑战. 了解这些不同的莱什曼病对于改善公共卫生战略和研究至关重要.
科学领域:
- 寄生虫学的寄生虫学
- 传染性疾病 传染性疾病
- 兽医医学 兽医医学 兽医医学
背景情况:
- 莱什曼病呈现出各种不同的临床形式,由各种莱什曼病物种和宿主引起.
- 新兴或非传统的Leishmania种群和非典型的呈现形式带来了诊断和治疗方面的挑战.
- 目前的监测和指导方针不足以解决未被认可的莱什曼病例.
研究的目的:
- 系统地绘制非传统和新兴Leishmania感染的不断变化的景观.
- 确定非典型莱什曼病所带来的诊断和治疗挑战.
- 为未来的研究,监测和公共卫生政策提供信息.
主要方法:
- 按照乔安娜·布里格斯研究所 (JBI) 和PRISMA-ScR指南进行系统审查.
- 在多个数据库 (PubMed,Embase,Cochrane等) 中进行搜索. 和灰色文学.
- 包括对非典型的人类表现,非传统物种和相关动物病例的研究;双重独立查和数据提取.
主要成果:
- 数据综合将涉及描述性统计,表格,图表和主题综合.
- 识别研究缺口,以指导未来的调查.
- 结果将通过同行评审的出版物和会议演讲传播.
结论:
- 需要对莱什曼病谱的全面了解.
- 这一审查将为临床医生,研究人员和政策制定者提供关键的见解.
- 将强调未来研究,诊断和监测的优先事项.
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