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迷走神经刺激的主要腹部表现:说明案例
Noah M Yaffe1, Eric Z Herring2, Kerrin S Sunshine2
1School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Journal of neurosurgery. Case lessons
|September 22, 2025
概括
神经刺激 (VNS) 可以导致严重的胃肠道问题和的儿童的尿路保留. 禁用VNS设备解决了这些不常见的副作用,这表明与神经信号干扰的联系.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 胃肠病学 胃肠病学
背景情况:
- 阴道神经刺激 (VNS) 是一种治疗难治性的治疗方法.
- 常见的VNS副作用包括咳,声和部疼痛.
- 与VNS相关的显著胃肠道症状尚未得到充分记录.
研究的目的:
- 报告儿科患者在VNS后出现严重的胃肠道和尿道症状的情况.
- 突出VNS可能导致这些不良影响的潜在机制.
主要方法:
- 一名患有早期婴儿性脑病的13岁女性接受了VNS系统.
- 患者经历腹部疼痛,便秘,减少口服摄入量,并在VNS启动后保持尿液.
- 六个月后,VNS设备被停用,导致症状消失.
主要成果:
- 患者出现了严重的胃肠道疾病,包括腹痛,便秘恶化和口腔厌恶.
- 在患者身上也观察到尿.
- 停止VNS导致所有报告的症状完全消失.
结论:
- 静脉神经系统可能会影响阴道信号传递,可能会破坏疼痛调节,并导致胃肠动.
- 迷走神经束布局的异质性,目前的外科手术技术没有解决,可能会导致各种VNS效应.
- 对于进行手术的外科医生来说,意识到这种与VNS相关的症状综合体至关重要.
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