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Updated: Jun 19, 2026

Isolation of Murine Peritoneal Macrophages to Carry Out Gene Expression Analysis Upon Toll-like Receptors Stimulation
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使用RNA-seq的Toxocara canis幼虫在体外宏环乳暴露的转录反应

Theresa A Quintana1, Matthew T Brewer2, Jeba R J Jesudoss Chelladurai1

  • 1Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA.

International journal for parasitology. Drugs and drug resistance
|September 22, 2025
PubMed
概括

宏循环乳 (MLs) 在Toxocara canis幼虫中广泛影响基因表达,影响关键的生物过程. 这项研究揭示了ivermectin和moxidectin如何改变寄生虫基因调节,为药物耐药性机制提供了新的见解.

关键词:
携带ATP结合的磁带传送器狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗狗谷氨酸化通道通过谷氨酸化通道.我从来没有做过任何事情.莫克西德克提因是一种氧化物.在RNA-Seqq.托克索卡拉犬是什么意思毒性病是一种毒性病.转录组 转录组就是一个转录组.它们是mRNARNA.

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RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...