在患有胃衰竭的患者中,失败的甲状腺排水程序的管理
1Department of Surgery, Washington University in St. Louis School of Medicine, St. Louis, MO, United States.
概括
当甲状腺排水因胃衰竭 (GP) 而失败时,本综述为评估和治疗提供了一个结构化的途径. 它指导临床医生通过耐火性GP的诊断和救援选择,改善患者的治疗结果.
科学领域:
- 胃肠病学 胃肠病学
- 手术创新 在外科创新.
- 医学算法 医学算法
背景情况:
- 耐火性胃衰竭 (GP) 往往需要胆囊排水程序,如胆囊整形或胃口腔内镜肌切除术 (G-POEM).
- 很大一部分患者经历了这些干预后的初级或二级失败,需要进一步的管理策略.
- 目前基于证据的指导在GP管理失败的甲状腺排水是有限的,创造了结构化的护理途径的需要.
研究的目的:
- 综合当前关于在失败的甲状腺排水后对胃衰竭 (GP) 患者的评估和治疗的数据.
- 提出一个务实的,以算法为导向的途径,用于多学科的护理在失败的胆道排水的情况下.
- 确定不良结果的预测因素,并概述耐火性胃衰竭的救援干预措施.
主要方法:
- 对2000年1月至2025年7月的英语文学进行了结构化的叙事审查.
- 搜索包括PubMed,Embase和Cochrane数据库,使用关键词与胃衰竭,胆囊排水程序和治疗失败有关.
- 选择了40多项相关研究来提取有关故障预测因素,诊断策略和救援干预措施的数据,这些数据被集成到算法中.
主要成果:
- 在胃衰竭 (GP) 中临床和客观失败的定义是多元的.
- 预测不良结果的预测因素包括年轻的年龄,更高的症状负担,更长的疾病持续时间,更高的BMI和持续的胃缩.
- 挽救方案包括重复G-POEM,胃电刺激,带通气胃口的结肠切除术,Roux-en-Y胃绕道或近乎全胃切除术,根据个体患者的生理学和症状量身定制.
结论:
- 失败的甲状腺排水突出显示了胃 (GP) 的复杂,多机理性质.
- 整合症状评估,客观测试和分阶段干预的结构化算法可以个性化对耐火GP的护理.
- 需要进一步的研究来规范失败标准,并对救援干预措施进行比较有效性试验.
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