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Updated: Jun 17, 2026

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通过NR3C1介导的表观遗传调节抑制了小鼠的天体细胞免疫反应

Seongwan Park1, Hyeonji Park1,2, Youkyeong Gloria Byun1

  • 1Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.

Nature communications
|September 22, 2025
PubMed
概括

NR3C1调节早期的星球细胞发育,影响长期的大脑免疫反应. 在早期发育过程中,NR3C1的丧失会使星体细胞在以后的生活中产生炎症.

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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...