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Updated: Jan 17, 2026

Combining 3D Magnetic Force Actuator and Multi-Functional Fluorescence Imaging to Study Nucleus Mechanobiology
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在受限细胞迁移中的核破裂触发了核活性聚合,以限制染色质泄漏

Christos Kamaras1, Dennis Frank2, Hong Wang2,3

  • 1Institute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty, University of Freiburg, 79104, Freiburg, Germany. christos.kamaras@pharmakol.uni-freiburg.de.

The EMBO journal
|September 22, 2025
PubMed
概括

细胞迁移期间核膜破裂触发了活性蛋白的形成,加强了细胞核. 这种ATR-胺通路可以防止染色质泄漏,并保持基因组稳定性,这对于理解癌症转移至关重要.

关键词:
癌细胞入侵 癌细胞入侵核动氨酸是核动氨酸中的一种.核力学 核力学 核力学

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