在左上四肢而不是右上四肢中,较高的缩血压差异与社区人口的全因死亡风险有关
Min Li1, Fangfang Fan1,2, Jia Jia1,2
1Department of Cardiology, Peking University First Hospital, Beijing, China.
概括
显著的双臂间静态血压差异 (IASBPD) 会增加死亡风险. 具体来说,左臂的IASBPD较高与所有原因死亡率的增加密切相关.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 双臂间静态血压差异 (IASBPD) 是心血管风险的潜在指标.
- 以前的研究表明,IASBPD与不良健康结果之间存在联系,但具体的关联需要进一步调查.
研究的目的:
- 调查中国社区队列中IASBPD和死亡风险之间的关联.
- 确定IASBPD的大小和方向是否影响所有原因和心血管死亡率.
主要方法:
- 分析了8628名中国社区居民的队列.
- 计算IASBPD的方法是将左臂缩血压从右臂缩血压减去.
- 参与者根据IASBPD 血压 (<10 mmHg或≥10 mmHg) 和特定手臂差异进行分类,死亡终点追踪时间中位数为9.87年.
主要成果:
- 与IASBPD患者≥10 mmHg组相比,IASBPD患者≥10 mmHg组的死亡风险增加了53%,心血管死亡风险增加了71%.
- 左臂的缩血压高于右臂的>10 mmHg显著与全因死亡风险增加59%相关.
- 在右臂高于≥10 mmHg或左臂高于≤10 mmHg的情况下,没有观察到死亡风险的显著增加.
结论:
- 升高的IASBPD显著与所有原因和心血管死亡率的风险增加有关.
- 双臂间的缩血压差异较大,特别是左臂较高时,表明全因死亡风险较高.
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