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ADPO:自动区分辅助的参数优化

Rong Chen1, Mark Sale2, Alex Mazur2

  • 1Data Sciences Software Division, Certara Inc., 4 Radnor Corporate Center, Suite 350, Radnor, 19087, PA, USA. rong.chen@certara.com.

Journal of pharmacokinetics and pharmacodynamics
|September 22, 2025
PubMed
概括

自动分化 (AD) 现在在城NLME 8.6中,显著加快了药理动力学/药理动力学 (PK/PD) 模型分析. 这种新方法,即自动区分辅助参数优化 (ADPO),与传统方法相比,可减少20-50%的计算时间.

关键词:
自动差异化自动差异化一个双数的数字.一个人的脸,一个人的脸.有限差异 有限差异.在PK/PD中,PK/PD是最常见的.参数估计的参数估计.

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