亚致命的特布可纳暴露增强了Sclerotium rolfsii的致病性和耐药性发展
Ruiping Huang1,2,3,4, Lin Zhou2,3,4, Xuewei Mao2,3,4
1College of Agriculture, Henan University, Kaifeng, China.
Pest management science
|September 23, 2025
概括
亚致命的特布可纳暴露可以增加Sclerotium rolfsii中的芽和毒性. 这种杀菌剂的应用也可能增强向基因表达,可能导致抗药性发展.
科学领域:
- 农业科学 农业科学
- 菌类学 菌类学是指菌类学.
- 毒理学 毒理学 毒理学
背景情况:
- 铁布可纳是一种三类杀菌剂,用于控制由Sclerotium rolfsii引起的花生南部病变.
- 有限的机理学研究存在于tebuconazole对S. rolfsii.的毒理学影响.
- 这项研究调查了tebuconazole对S. rolfsii生长,毒性和分子机制的影响.
研究的目的:
- 为了评估亚致命的tebuconazole度对Sclerotium rolfsii的影响.
- 为了了解S. rolfsii在暴露于tebuconazole时的分子反应.
- 提供关于tebuconazole在花生疾病管理中的科学应用的指导.
主要方法:
- 对S. rolfsii暴露于不同度的铁布可纳 (EC10,EC25,EC30).
- 评估结核菌的发芽速度和细胞膜的透性.
- 测量抗氧化酶活性和目标基因 (SrCYP51) 表达.
主要成果:
- 亚致命的铁布可纳增加了硬质细胞发芽率和酸分泌.
- 德布可纳暴露最初减少,然后增加细胞膜的透性.
- 抗氧化酶活动和SrCYP51基因表达在特布可纳压力下升调.
结论:
- 德布可纳可能会诱导发芽,增强毒性,并上调S. rolfsii.中的基因表达.
- 这些影响对疾病控制和杀菌剂耐药性构成风险.
- 这些发现有助于更好地了解特布可纳的毒性,并为控制策略提供信息.
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