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B细胞急性淋巴细胞白血病呈现双边扩大
Omolayo Soruna1, Muniba Qureshi1, Mani Prabha2
1Paediatrics and Child Health, Mid and South Essex NHS Foundation Trust, Essex, GBR.
Cureus
|September 23, 2025
概括
这项案例研究突出了B细胞急性淋巴细胞白血病 (ALL) 的儿童脏透的罕见情况. 迅速的化疗解决了壮症,强调ALL作为儿科腹部质量的差异诊断.
科学领域:
- 儿科瘤学 儿科瘤学
- 血液学 血液学 血液学
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 急性淋巴细胞白血病 (ALL) 是最常见的儿童癌症.
- 已知ALL的外脊髓表现,但脏透异常罕见.
- 患有腹部质量和发烧的儿科患者需要广泛的差异诊断.
研究的目的:
- 报告一例罕见的双边脏白血病透病例,发生在患有B细胞ALL的儿科患者身上.
- 讨论临床表现,诊断发现和这种不常见的ALL表现的管理.
- 强调在儿童壮症的差异诊断中考虑ALL的重要性.
主要方法:
- 一个一岁的女孩患有B细胞ALL的病例报告.
- 临床检查,实验室检查 (血液计数,尿液分析),周围血液膜和流细胞测量用于诊断.
- 超声波用于成像脏干扰.
- 在化疗期间监测功能,液体平衡和血压.
主要成果:
- 患者呈现出发烧,昏迷和腹部张张,双侧腹部质量.
- B细胞ALL的诊断证实与白细胞瘤和细胞衰减.
- 超声波检查显示双边扩大 (缩),暗示白血病透.
- 尽管有巨大的壮病,功能,液体平衡和血压仍然正常.
- 多种药物化疗开始后四周内,瘤缩症得到缓解.
结论:
- 在ALL中,脏参与是一种不常见的外表现,通常无症状.
- 在ALL中脏的白血病透通常不会损害功能.
- 在ALL中壮症通常没有不良的预后意义,并通过化疗缓解.
- 这一案例强调了需要考虑儿科患者的ALL,这些儿科患者有不明原因的壮症或腹部质量.
- 密切监测瘤溶解综合征对于管理脏ALL至关重要.
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