末性牙周病:流行病学,临床特征和病原发生
Alex Nogueira Haas1, Shadoe Stewart2, Cristiano Susin2
1Periodontology, Faculty of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Journal of periodontal research
|September 23, 2025
概括
末性牙周病 (NPDs) 是一种机会性感染,与口腔生物膜和诸如营养不良和艾滋病毒等诱导因素有关. 虽然与牙周炎不同,但它们的确切病理生理学需要进一步研究.
科学领域:
- 口腔医学是指口腔医学.
- 牙周病学 牙周病学
- 传染性疾病 传染性疾病
背景情况:
- 末性牙周病 (NPDs) 包括末性牙周炎,末性牙周炎,末性牙周炎和 noma.
- 这些疾病的特点是牙,牙周和口腔粘膜缩,疼痛,炎症和出血.
研究的目的:
- 审查死性牙周病 (NPD) 的流行病学,病因学和病原性.
- 为NPD发展提出一个因果途径模型.
主要方法:
- 流行病学,病因学和病原学的文献综述.
- 进行元分析以估计患病率.
- 对NPDs的因果途径模型的开发.
主要成果:
- 死亡性牙周炎的患病率估计为0.04%,拉丁美洲,亚洲,艾滋病毒阳性个体和吸毒者患病率更高.
- 新发病症在年轻人和严重营养不良的人群中更为普遍.
- 诱导因素包括免疫抑制,压力,营养不良,吸烟,酒精,糖尿病和艾滋病毒.
结论:
- 无牙周病是机会性感染,需要先前存在的牙炎/牙周炎和易感因素.
- 在现象上,NPD与常规牙周炎有所区别,但病理生理差异尚不清楚.
- 需要进一步的研究来了解NPDs的潜在生物机制.
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