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Updated: Jan 17, 2026

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor
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SARS-CoV-2 NSP13与TEAD相互作用,以抑制Hippo-YAP信号传递

Fansen Meng1, Jong Hwan Kim2, Chang-Ru Tsai3

  • 1McGill Gene Editing Lab, The Texas Heart Institute, Houston, United States.

eLife
|September 23, 2025
PubMed
概括

严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 非结构蛋白13 (NSP13) 抑制YAP/TEAD介导的基因表达,影响器官发育. 这种病毒蛋白干扰Hippo-YAP通路,独立于上游激酶.

关键词:
哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈河马的路径 河马的路径在NSP13中,您可以使用NSP13.这就是SARS-CoV2病毒.我们的 TEAD TEAD 团队.哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈这是心肌细胞 (cardiomyocytes).细胞生物学 细胞生物学这里是鼠标鼠标鼠标鼠标鼠标鼠标.病毒病毒病毒病毒.

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