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关于"用纵向数据进行临床试验分析的新型非线性模型:使用SAS用于频率主义和贝叶斯方法的教程"的评论

Guoqiao Wang1, Guogen Shan2, Yan Li1

  • 1Department of Neurology, Washington University in St Louis, St. Louis, Missouri, USA.

Statistics in medicine
|September 23, 2025
PubMed
概括

反复测量比例混合模型 (pMMRM) 为使用纵向数据推断临床试验疗效提供了更大的统计能力. 这种方法提供了一种灵活的方法来分析多次研究访问,与传统差异方法相比,增强了功率.

关键词:
这是一个不对称的分布.无异常无偏的不偏见."三角洲法"是什么意思?相对比例的MMRM.治疗效果的比例治疗效果.

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