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Updated: Jan 17, 2026

DNA Polymerase Activity Assay Using Near-infrared Fluorescent Labeled DNA Visualized by Acrylamide Gel Electrophoresis
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DNA Polymerase Activity Assay Using Near-infrared Fluorescent Labeled DNA Visualized by Acrylamide Gel Electrophoresis

Published on: October 6, 2017

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DNA聚合酶卡帕是化物ICLs的主要转化合成聚合酶

Roxanne V van der Sluijs1,2,3, Alexander E E Verkennis1,2,3, Michael R Hodskinson4

  • 1Oncode Institute, 3521 AL Utrecht, The Netherlands.

Nucleic acids research
|September 23, 2025
PubMed
概括

从化物中得到的DNA跨链交叉连接 (ICL) 通过两种途径进行修复. DNA聚合酶卡帕 (Polκ) 是通过转化合成绕过化物ICL的关键,与其在其他ICL修复中的作用不同.

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