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健康查中的间歇性肺异常检查:患病率,结果和危险因素

Jooae Choe¹, Ju Hyun Oh², Han Na Noh³

¹Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Journal of Korean medical science

|September 23, 2025

概括

间歇性肺部异常 (ILA) 的患病率很低,但随着年龄的增长,亚洲成年人患病率会增加. 渐进性ILA与较高的死亡率有关,年龄和吸烟是关键的危险因素.

科学领域:

肺部医学肺部医学
放射学放射学是一门学科.
流行病学流行病学

背景情况:

在亚洲人群中,间歇性肺异常 (ILA) 的患病率,结果和风险因素尚不清楚.
调查ILA对于了解其对不同种族群体公共卫生的影响至关重要.

研究的目的:

确定亚洲人口中间歇性肺异常 (ILA) 的患病率和进展情况.
为了确定与渐进性ILA相关的基线风险因素.
评估ILA与全因死亡率之间的关联.

主要方法:

以5年间隔进行连续胸部计算机断层扫描 (CT) 的健康检查参与者的回顾性分析.
使用CT成像评估ILA的存在和时间变化.
多变量后勤回归用于识别渐进性ILA的风险因素.

主要成果:

从基线到随访期间,ILA或模两可的ILA的患病率显著增加 (分别为0.2%至0.8%和0.3%至0.9%).
在基线ILA病例的83.3%中观察到ILA的放射性进展.
高龄,吸烟史,白细胞计数升高,红细胞沉积率和类风湿性因素是渐进性ILA的独立风险因素.
ILA和模两可的ILA都与所有原因死亡率的增加显著相关,而渐进的ILA进一步增加了死亡风险.

结论:

中年韩国人的ILA患病率较低,但随着年龄的增长而增加,并与长期死亡率有关.
ILA的放射性进展很常见,风险因素包括年龄,吸烟和炎症标志物.
在风险人群中早期发现和监测ILA对于改善长期健康结果至关重要.

关键词:

计算机断层扫描 (CT) 是一种计算机断层扫描.间歇性肺部异常间歇性肺部异常间歇性肺部疾病间歇性肺部疾病实验室测试实验室测试实验室测试风险因素风险因素

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