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焦虑中的奖励处理中断:fMRI证据表明易受挫折的脆弱性,没有奖励

Jiaming Wan¹, Yijia Zhou², Xukai Zhang²

¹School of Psychology, https://ror.org/01kq0pv72South China Normal University, Guangdong, China.

Psychological medicine

|September 23, 2025

概括

患有焦虑症的人在低丧时表现出正常的奖励处理,但与令人丧的非奖励作斗争,导致不适应模式. 这强调了焦虑.

科学领域:

神经科学是一个神经科学.
心理学心理学心理学
认知科学认知科学

背景情况:

焦虑是一种持续的特征,影响功能和增加风险.
奖励处理是焦虑研究的一个关键领域.
焦虑的个体可能会表现出改变的奖励处理,特别是在丧的情况下.

研究的目的:

研究高焦虑 (HA) 和低焦虑 (LA) 组之间的奖励处理差异.
为了检查挫折的非奖励对焦虑中的认知和情绪处理的影响.
在焦虑中识别适应不良奖励处理的神经相关物.

主要方法:

使用了功能磁共振成像 (fMRI).
招募了66名参与者 (33个HA,33个LA).
在fMRI扫描期间模拟了令人丧的非奖励.

主要成果:

在低挫折状态下,HA组在注意力重定位期间显示出可比的准确性和视觉和认知控制区域的更大激活.
在高度丧的情况下,HA组的准确性明显较低.
在HA组中,在高度丧的认知情感控制大脑区域内观察到不适应的信息处理模式.

结论:

焦虑与两个不同的奖励处理模式有关,在不同的丧水平下形成对比.
这些发现加深了对焦虑中奖励处理机制的理解.
这项研究提供了对焦虑中认知处理中断的危险因素的见解.

关键词:

焦虑是一种焦虑.功能磁力共振成像 (fMRI) 是一种令人丧的非奖励.奖励处理奖励的处理.

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Anxiety: Overview

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Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.