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Updated: Jan 6, 2026

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对I型猫科冠状病毒具有后吸附阻断活性的中和单克隆抗体的表征

Tomoyoshi Doki1, Kazuki Kanasaki1, Nobuhisa Hasegawa1

  • 1Laboratory of Veterinary Infectious Disease, School of Veterinary Medicine, Kitasato University, 034-8628, Towada, Aomori, Japan.

Archives of virology
|September 23, 2025
PubMed
概括

研究人员开发了Ya-NT-1,这是第一种针对猫科冠状病毒I型 (FCoV-I) 的中和抗体,为猫科传染性周周炎 (FIP) 提供了潜在的新疗法. 这种抗体针对FCoV-I进入后,为FIP疗法铺平了道路.

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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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