调查环境空气污染暴露与双胞胎怀孕中异常妊娠体重增加之间的关系:一项回顾性研究
Wei-Zhen Tang1,2,3, Zhe-Ming Kang1,2,3, Qin-Yu Cai2,3
1Department of Obstetrics and Gynecology, Women and Children's Hospital of Chongqing Medical University, Chongqing, 401147, China.
在双胞胎怀孕中,空气污染对妊娠期体重增加 (GWG) 的影响在三个月内不同. 微粒颗粒物 (PM2.5) 和其他污染物在早期对不充分的GWG构成风险,但可以在怀孕后期防止过度的GWG.
科学领域:
- 环境健康 环境健康
- 产妇胎儿医学 产妇胎儿医学
- 产科和妇科 产科和妇科
背景情况:
- 孕期体重增加 (GWG) 对母亲和胎儿的健康至关重要.
- 关于空气污染对双胞胎怀孕中异常GWG的影响的了解有限.
研究的目的:
- 调查在双胞胎怀孕中暴露于环境空气污染物和GWG之间的关联.
- 分析空气污染如何影响不同孕期的不充分和过度GWG.
主要方法:
- 对3598例双胞胎怀孕的回顾性分析.
- 收集了各种空气污染物 (PM2.5,PM10,SO2,NO2,CO,O3) 的数据.
- 多变量和后勤回归模型用于评估污染物对GWG的影响和异常增益的风险,考虑三月期特定的暴露.
主要成果:
- 暴露于PM2.5,PM10,SO2,NO2和CO与GWG正相关;O3与GWG负相关.
- 不充分的GWG与第一季度的PM2.5,PM10和SO2以及第三季度的O3有关.
- 过度的GWG风险在三个月内受到污染物的不同影响,PM2.5,PM10,SO2和CO成为后三个月的风险因素,而O3显示出保护作用.
结论:
- 环境空气污染物对双胞胎怀孕中的GWG具有特定阶段的影响.
- 极端空气污染暴露表明影响GWG结果的时间依赖性特征.
- 这些发现强调了空气质量和双胞胎怀孕中母亲体重增加之间的复杂,三个月的特定关系.
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