在瑞典,月经前障碍和生活质量
Qiwei Wang1, Rebecka Keijser1, Yufeng Chen1
1Unit of Integrative Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
JAMA network open
|September 23, 2025
概括
月经前障碍 (PMDs) 显著降低女性的生活质量 (QOL),而月经前失调障碍 (PMDD) 的影响比月经前综合征 (PMS) 更大. 这些发现强调需要对受影响妇女进行更好的管理和支持.
科学领域:
- 生殖健康 生殖健康
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 月经前障碍 (PMDs),包括月经前综合征 (PMS) 和月经前失调障碍 (PMDD),给人带来了相当大的身体和心理负担.
- 对于PMD对生活质量 (QOL) 的影响尚不完全理解,尤其是在考虑并发症和混因素时.
研究的目的:
- 评估和比较在瑞典被诊断患有PMD的女性的QOL与没有PMD的女性的QOL.
- 调查PMS,PMDD和质量生活的各种维度之间的特定关联.
主要方法:
- 一项利用瑞典基于人口的LifeGene队列进行的横截面研究,与国家卫生登记处联系在一起.
- 使用修改后的月经前症状查工具识别了PMD,并通过医疗保健登记册诊断证实了PMD.
- 使用EuroQol5维3级尺度测量QOL,根据人口统计和社会经济因素调整分析,并按并发病史分层.
主要成果:
- 在17284名女性中,有10.5%患有PMD. 患有PMD的女性报告QOL显著降低 (平均z分数差异:0.21).
- 在前性分析和排除焦虑/抑郁和疼痛/不适的维度后,PMD和QOL之间的负相关性仍然显著.
- PMDD与QOL的负相关性比PMS更强. PMD与焦虑/抑郁和疼痛/不适有显著的联系.
结论:
- 月经前障碍,特别是PMDD,与女性的QOL降低密切相关,不论是混杂因素和并发症.
- 这些发现强调了综合医疗保健和社会支持系统的必要性,以加强PMD妇女的管理和整体福祉.
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