与COVID-19老年患者的死亡率相关的临床参数
Mehmet Gökhan Kaya1, Kıvanç Karaman2
1Emergency Medicine Service, Mugla Training and Research Hospital, Mugla, Turkey.
PloS one
|September 23, 2025
概括
年长的COVID-19患者.
科学领域:
- 紧急医疗 紧急医疗
- 老年病的医生 老年病的医生
- 传染性疾病 传染性疾病
- 关键的护理关键的护理
背景情况:
- 老年COVID-19患者具有严重后果和死亡的高风险.
- 在急诊室 (ED) 中,早期风险分层是至关重要的.
- 临床参数如呼吸速率,氧和和外周 perfusion 指数 (PPI) 显示出死亡风险评估的潜力.
研究的目的:
- 评估临床参数与老年COVID-19患者住院死亡率的相关性.
- 为了确定外周 perfusion 指数 (PPI),呼吸速率和氧和在风险分层中的有效性.
主要方法:
- 在土耳其一所大学医院对144名65岁以上的COVID-19患者进行了回顾性研究.
- 从医疗记录中收集了生命体征,休克指数和PPI.
- 使用的接收器操作特征 (ROC) 曲线和二进制物流回归分析.
主要成果:
- 37 (26%) 患者在住院期间死亡.
- PPI ≤ 2.20 确定患有较低死亡风险的患者 (AUC=0.684,敏感度=75.7%).
- 氧和率 ≤ 86% 确定高风险患者 (特异性=79.4%,PPV=46.3%). 呼吸速率≥25次/分钟也与死亡率相关 (AUC=0.652).
- 低PPI与死亡率增加独立相关 (OR=4.067,p=0.002).
结论:
- 随时可用的临床参数,包括PPI,呼吸速率和氧和,与老年COVID-19患者的死亡率密切相关.
- 这些参数可以增强ED分拣协议,以便早期识别高风险个体.
- 需要进一步的前性研究来验证这些发现,以对急性护理风险分层进行验证.
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