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Updated: Jan 17, 2026

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在Hi-C接触矩阵上随机走路可以提高数据质量吗? 一个评估评估一个评估

Yongqi Liu1, Shili Lin1

  • 1Department of Statistics, The Ohio State University, Columbus, Ohio, United States of America.

PloS one
|September 23, 2025
PubMed
概括

随机步行改善Hi-C数据质量的方法,如随机步行与步骤 (RWS) 和随机步行与重启 (RWR),对于识别拓关联域 (TAD) 显示最小的好处. 研究人员在下游分析之前应该谨慎使用这些方法.

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