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相关概念视频

Overview of Exosomes01:36

Overview of Exosomes

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Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
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Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes
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Using Nanoplasmon-Enhanced Scattering and Low-Magnification Microscope Imaging to Quantify Tumor-Derived Exosomes

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表面增强的拉曼光谱用于外体形:方法和应用.

Yang Cheng1, Jiayi Wang1, Qihan Zhang1

  • 1Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, PR China.

Talanta
|September 23, 2025
PubMed
概括

表面增强拉曼光谱 (SERS) 提供了分析外体的强大方法,外体是关键的生物标志物. 本综述探讨了SERS在外体指纹和生物标志物分析中用于疾病诊断和来源追踪的应用.

科学领域:

  • 生物技术是生物技术.
  • 频谱学是一种光谱学.
  • 纳米技术 纳米技术

背景情况:

  • 外体是携带细胞载荷的纳米级囊泡,由于它们的起源特征,它们对液体活检非常有价值.
  • 外体样本分析对于生物标志物发现和疾病诊断至关重要.

研究的目的:

  • 审查现有表面增强拉曼光谱 (SERS) 的方法和应用,用于外体形.
  • 突出基于SERS的外体细胞指纹和生物标志物分析策略.

主要方法:

  • 用于外体细胞指纹的SERS基质的分类.
  • 重点是针对外体组分析的定制策略.
  • 对生物标志物发现的无标签SERS方法的审查.

主要成果:

  • 通过指纹检测,SERS可以追踪外体源和诊断疾病.
  • 使用SERS检测外体蛋白和核酸.
  • 在无标签SERS中取得的进步,用于生物标志物发现.

结论:

  • SERS是一种有前途的技术,可用于全面的外体样分析.
  • 需要进一步开发,以应对挑战,并扩大SERS在液体活检和诊断中的应用.
关键词:
对外体生物标志物进行剖析.外体指纹的指纹采集外基因组是外基因组的组成部分.液体活检液体活检表面增强的拉曼光谱学 (SERS)

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An Innovative Method for Exosome Quantification and Size Measurement
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An Innovative Method for Exosome Quantification and Size Measurement

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Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets
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Multimodal Analytical Platform on a Multiplexed Surface Plasmon Resonance Imaging Chip for the Analysis of Extracellular Vesicle Subsets

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