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Updated: Jan 17, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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ATP-NLRP3炎症酶轴增强了髓质衍生抑制细胞的免疫抑制作用

Tatsuya Ando1, Kouhei Sakurai1, Masato Hoshi2

  • 1Department of Joint Research Laboratory of Clinical Medicine, Fujita Health University School of Medicine, Aichi 470-1192, Japan.

Immunobiology
|September 23, 2025
PubMed
概括

骨髓系衍生抑制细胞 (MDSCs) 阻碍了免疫检查点抑制剂. 针对MDSC中的腺三酸盐 (ATP) -NLRP3炎症酶轴可以恢复抗瘤免疫力并提高癌症免疫疗法的疗效.

关键词:
亚丁酸三酸盐是一种氨酸三酸盐.组合疗法是一种联合疗法.免疫抑制作用 免疫抑制作用来自骨髓细胞的抑制细胞.在NLRP3炎症酶体中,NLRP3炎症

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