唾液功能与喉回流之间的关联是客观地测量的
So Young Jeon1, Hwa Sung Rim1, Yeonseo Lee2
1Department of Otolaryngology-Head & Neck Surgery, Kyung Hee University School of Medicine, Kyung Hee University Medical Center, Seoul, Korea.
Journal of voice : official journal of the Voice Foundation
|September 23, 2025
概括
这项研究发现,在患有喉回流 (LPR) 和没有喉回流 (LPR) 的患者之间,唾液流率 (SFR) 没有显著差异. 在这个患者队列中,唾液功能似乎与LPR症状无关.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 胃肠病学 胃肠病学
- 生理学 生理学 生理学
背景情况:
- 喉回流 (LPR) 是一种胃酸上升到喉的情况.
- 唾液功能,以唾液流速 (SFR) 衡量,在保护喉和食道方面发挥作用.
- SFR和LPR之间的关系尚未得到广泛的研究.
研究的目的:
- 调查症状患者的唾液功能 (SFR) 和LPR之间的关联.
- 为了在被诊断为LPR的患者中比较SFR与没有LPR的患者.
主要方法:
- 患有LPR症状的患者接受了24小时的下-食道多通道内阻抗-pH (24-h-HEMII-pH) 监测.
- 在所有患者中测量了唾液流速 (SFR).
- 在LPR和非LPR组之间进行了SFR比较.
主要成果:
- 在80名患者中,67名 (84%) 被诊断出患有LPR.
- 在非刺激的SFR中没有发现显著差异 (0.48毫升/分钟在LPR中与0.52毫升/分钟在非LPR中,P=0.735).
- 在刺激的SFR (2.5毫升/分钟在LPR与2.3毫升/分钟在非LPR,P=0.610) 没有发现显著差异.
- 反流症状指数 (RSI) 在LPR或非LPR患者中,正常和异常SFR组之间没有显著差异.
结论:
- 根据SFR评估的唾液功能,在患有和没有LPR的患者之间没有显著差异.
- 这项研究表明,唾液功能低下与LPR存在之间没有直接关联.
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