极端友微生物可以容忍高度的稀土元素 (REEs)
Hannah S Zurier1, Chloe Hart2, Stephanie Napieralski2
1Department of Chemical Engineering, Columbia University, New York, United States.
Biotechnology letters
|September 23, 2025
概括
与普通细菌不同的是,极端的酸性菌种可以容忍高度的稀土元素 (REE). 这一发现是开发可持续生物技术的关键,用于REE提取和净化.
科学领域:
- 生物技术和环境科学 生物技术和环境科学
- 微生物生理学和极端动物
背景情况:
- 对稀土元素 (REEs) 的需求不断增长,需要可持续的生物技术解决方案来提取和净化.
- 识别耐受高REE度的坚固底盘生物对于开发有效的生物采矿技术至关重要.
- 目前的研究表明,中性友好性介质细胞对REE表现出敏感性,限制了它们在REE生物处理中的使用.
研究的目的:
- 评估不同微生物底盘生物对高度稀土元素 (REEs) 的耐受性.
- 为了确定REE生物采矿应用的潜在候选微生物.
- 在REE暴露的背景下了解极端动物的压力耐受机制.
主要方法:
- 增长抑制试验是在REEs的不同介质条件下对美索菲尔大肠杆菌和Pseudomonas alloputida进行的.
- 确定了REE的半最大抑制度 (IC50) 对这些中性动物有机体.
- 评估了极端酸性动物 (Acidithiobacillus物种) 和高热性酸性动物 (Sulfolobus acidocaldarius) 对高REE度的耐受性.
主要成果:
- 在复杂的介质中,美索菲尔大肠杆菌在300μM REEs以下显示出有限的抑制,但在酸盐贫乏的最小介质中,其IC50为80 ± 100μM.
- 伪虫alloputida表现出增长障碍,其IC50为100 ± 20μM REE.
- 极端酸性菌 (Acidithiobacillus物种) 和 Sulfolobus acidocaldarius表现出显著的耐受性,在没有增长抑制的情况下承受500微米的REEs;有些甚至表现出增长的增强.
结论:
- 极端的酸性恋者对高稀土元素 (REE) 度具有固有的耐受性机制,与敏感的中性恋者不同.
- 这些酸性微生物是开发可再生能源提取和加工可持续生物技术的有希望的候选者.
- 极端动物的广泛耐压力表明,在生物技术应用中可能有更广泛的适应性.
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