习惯性饮食与骨肌肉组成的关联在一个横截面,基于人口的成像研究中
Susanne Rospleszcz1,2,3, Theresa Burger4,5, Nuha Shugaa Addin6,4,7
1Department of Diagnostic and Interventional Radiology, Faculty of Medicine, University Medical Center Freiburg, University of Freiburg, Killianstr 5a, Freiburg, 79106, Germany. susanne.rospleszcz@uniklinik-freiburg.de.
Nutrition journal
|September 23, 2025
概括
酒精和蛋白质摄入量会影响中年成人骨肌肉的组成. 较高的酒精消费与肌肉脂肪增加相关,而蛋白质可能会减少它,这表明饮食调整可以改善肌肉健康.
科学领域:
- 营养科学 营养科学
- 肌肉骨健康 肌肉骨健康
- 医疗成像医学成像
背景情况:
- 骨肌肉的健康对整体健康和功能至关重要.
- 有限的基于人口的研究存在于营养和肌肉组成 (质量,脂肪透) 之间的关系.
研究的目的:
- 调查能量营养素 (碳水化合物,脂肪,蛋白质,酒精) 和必需氨基酸与骨肌肉脂肪和面积的习惯性摄入之间的关联.
- 利用磁共振成像 (MRI) 来评估以人口为基础的中年人群的肌肉组成.
主要方法:
- 来自KORA-MRI研究的294名中年人 (45%为女性,平均年龄为56.5岁) 的分析.
- 肌肉脂肪百分比和肌肉面积 (cm2) 量化使用全身MRI与多回声迪克森序列.
- 习惯性饮食摄入量通过反复的24小时回忆和食物频率问卷进行评估,并进行相关性和回归分析.
主要成果:
- 酒精摄入量与骨肌肉脂肪增加有显著的关联,特别是在男性 (β=0.28%).
- 蛋白质摄入量暂时与肌肉脂肪减少有关 (β=-0.33%,p=0.052).
- 在考虑总体蛋白质和能量摄入时,特定的必需氨基酸,如白素,暂时与较低的肌肉脂肪有关.
结论:
- 习惯性饮酒和蛋白质消费与中年成人骨肌肉脂肪透有关.
- 饮食修改,特别是关于酒精和蛋白质摄入量,可能提供一种提高肌肉组成和功能的策略.
相关概念视频
01:55Bone Structure
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
01:40Bone Remodeling
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
01:29Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
01:09Changes in the Appendicular Skeleton with Age
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
01:20Introduction to the Skeletal System
The skeletal system is the central framework of the body, consisting of different connective tissues: bones, cartilage, tendons, and ligaments.
Components of the Skeletal System
Bone, or osseous tissue, is a hard connective tissue that forms an internal support structure for the human body. Bones shield vulnerable organs and soft tissue from external forces. For example, the vertebral bones protect and support the spinal cord.
Cartilage, a semi-rigid connective tissue found in regions such as...
Components of the Skeletal System
Bone, or osseous tissue, is a hard connective tissue that forms an internal support structure for the human body. Bones shield vulnerable organs and soft tissue from external forces. For example, the vertebral bones protect and support the spinal cord.
Cartilage, a semi-rigid connective tissue found in regions such as...
01:09Spongy Bone
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...