患者报告的关于静脉注射和口服抗生素治疗黄金杆菌菌病的看法,经验和偏好:一项描述性的定性研究
Genevieve Walls1, Loughlin McGrath1,2, Michael Trent Herdman1
1Department of Infectious Diseases, Middlemore Hospital, Te Whatu Ora Counties Manukau, Auckland 1640, New Zealand.
概括
患有严重感染的患者,如金黄色葡萄球菌菌病症经常喜欢口服抗生素的方便,尽管对有效性的担忧. 将患者的偏好纳入治疗决策对于更好的结果至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
- 定性研究是一种定性研究.
背景情况:
- 越来越多的证据支持部分口服抗生素治疗严重感染,包括黄金菌杆菌菌菌.
- 对严重感染的口服抗生素模式的临床采用落后于证据.
- 关于患者对静脉注射 (IV) 与口服抗生素的体验,关于生活质量和感知有效性的了解有限.
研究的目的:
- 探索患者对IV和口服抗生素治疗严重感染的观点.
- 收集对患者偏好和经验的见解,以告知协作治疗决策.
主要方法:
- 进行了半结构化采访,对17名接受治疗的患者进行了半结构化采访.
- 采访采用了电话,面对面和视频会议,采访分两个阶段进行 (2024年11月 - 2025年1月).
- 采用记录,转录和编码的采访数据的专题分析.
主要成果:
- 大多数患者更喜欢口服抗生素,因为方便,增强移动性和独立性.
- 参与者认为口服治疗方案比IV抗生素更复杂,可能会引起更多的副作用.
- 尽管方便,但人们仍然认为,静脉注射抗生素在临床上更有效.
结论:
- 对于严重的感染,选择抗生素给药途径需要平衡临床状况与患者的偏好和个人环境.
- 患者的便利性和功能目标是临床医生和患者之间的共同决策讨论中的重要考虑因素.
- 整合患者报告的结果和偏好可以优化严重感染的抗生素治疗策略.
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