在类风湿性疾病中对上肢陷神经病变的电生理学评估
Tuba Erdem Sultanoğlu1, Safinaz Ataoğlu
1Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Düzce University, Düzce, Türkiye.
Medicine
|September 24, 2025
概括
类风湿性疾病 (RDs) 中的系统性炎症可能会导致周围神经系统问题. 电子神经肌谱 (ENMG) 有助于早期诊断这些神经病变,对于管理RD并发症至关重要.
科学领域:
- 神经学 神经学
- 类风湿病学 类风湿病学
- 临床电生理学 临床电生理学
背景情况:
- 类风湿性疾病 (RDs) 中的系统性炎症可能导致周围神经系统并发症,包括神经病和肌病问题.
- 上肢陷神经病变很常见,但在RD患者中诊断不足.
研究的目的:
- 为了确定患有RDS的患者上肢陷神经病变的频率.
- 为了确定与这些神经病变相关的变量.
- 强调电神经图 (ENMG) 在早期检测和管理中的作用.
主要方法:
- 一项涉及102名被诊断患有RDS的患者的横截面研究.
- 收集人口,临床和实验室数据,包括疾病活动得分 (DAS28,DAS-PsA,EULAR-SSDI) 和炎症标志物 (ESR,CRP).
- 神经传导研究 (NCS) 根据美国神经学会的标准进行.
主要成果:
- 手腕道综合征的流行率为:风湿性关节炎 (RA) 的50%,牛皮性关节炎 (PsA) 的47.4%,Sjögren综合征 (SS) 的22.2%. 立方体道综合征发生在9.5%的RA患者中.
- 阳性ENMG发现与年龄相关,RD诊断,ESR,CRP,疾病活性,并发症,疾病持续时间和受影响的侧面.
- 顺序回归表明疾病持续时间,ESR,诊断,疾病活性和并发症对正常ENMG发现产生了负面影响,而受影响的侧面与ENMG结果有显著的关联.
结论:
- 周围神经病变,特别是手腕和肘部道综合征,在RD患者中很常见.
- 在RDS中,ENMG对于早期诊断,定位,严重程度评估和神经病变的预后至关重要.
- 临床医生应考虑在RD患者出现相关症状时对外围神经的参与.
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