脑电图缺血模式变化的预测价值对于缺血性心脏病的10年发生情况
Sara Saffar Soflaei1,2, Malihehsadat Abedsaeidi1,2, Eisa Nazar3
1Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
概括
静止心电图 (ECG) 异常可以预测中年成人未来的缺血性心脏病 (IHD). 轻微和重大心电图变化都表明IHD风险较高,但只有重大变化预测IHD死亡率.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 静止心电图 (ECG) 对预测无症状中年人缺血性心脏病 (IHD) 发病率和死亡率的长期预后价值尚未得到充分证实.
- 休息心电图是一种潜在的查工具,用于识别有风险的健康成年人.
研究的目的:
- 评估静止心电图上主要和次要缺血性变化的预后价值,以预测长期内脏病发病率和死亡率.
- 评估心电图作为中年无症状人群的查工具.
主要方法:
- 招募了9035名具有可用的心电图的中年受试者,并跟踪了10年.
- 使用明尼苏达州编码系统对ECG缺血进行了分类.
- 多重逻辑回归被用来分析ECG缺血变化与IHD发生之间的关联,p < 0.05被认为是显著的.
主要成果:
- 13.6%有重大,12.0%有轻微的缺血性心电图变化.
- 经过10年,8.3%的参与者患上IHD (124例死亡,623例幸存者).
- 大和小缺血变化都与较高的IHD发病率相关 (p=0.001),而只有大变化预测了IHD死亡率 (p=0.004),即使经过对混因素进行调整.
结论:
- 较小和较大的单独的心电图异常与中年成年人长期IHD发病率的增加有关.
- 脑电图上主要的缺血变化与因心脏病发作的死亡风险较高有关.
- 静止心电图的发现对无症状中年人群中IHD具有预后价值.
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