一个随机的临床试验比较鼻内利多卡因和盐水在胃镜检查之前
Elizabeth Alvey1, Langdon Fielding1, Dustin Dennis1
1Loomis Basin Equine Medical Center, Penryn, CA.
Open veterinary journal
|September 24, 2025
概括
这项研究发现,与盐水相比,使用鼻内利多卡因 (LID) 对马体检没有显著的益处. 随着LID的使用,内镜通道时间和马的反应能力都没有得到改善.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 马匹实践 马匹实践
- 胃肠病学 胃肠病学
背景情况:
- 鼻内利多卡因 (LID) 通常用于马匹,以缓解内镜和鼻管通道.
- 目前缺乏证据支持LID在马匹实践中的有效性.
研究的目的:
- 为了比较鼻内LID与盐水对马的反应性和胃镜检查期间内镜通道时间的影响.
主要方法:
- 一个盲目的随机临床试验,涉及25匹接受胃镜检查的马.
- 马在手术前接受了10毫升2%的鼻内LID或液.
- 收集的数据包括反应度等级和内镜从神经到心脏的通行时间.
主要成果:
- 在LID (70秒) 和盐水 (73秒) 组之间,心脏通过时间没有显著差异 (p=0.8).
- 观察到类似的低反应率:LID组的69%和盐酸组的75% (p=0.12).
结论:
- 这项研究没有证明鼻内LID与盐水相比有显著的益处,以促进马匹通过内镜.
- 用更大的样本大小进行进一步的研究可能是有必要的,以最终评估LID的作用.
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