帕金森病中的虚拟现实:系统性审查和元分析
João Vitor Andrade Fernandes1, Vera Louise Freire de Albuquerque Figueiredo1, Afonso Bezerra Oliveira1
1Universidade Federal da Paraíba, João Pessoa PB, Brazil.
Dementia & neuropsychologia
|September 24, 2025
概括
虚拟现实 (VR) 改善了帕金森病患者的动态平衡和移动性. 然而,它对静态平衡的影响是有限的,需要为更好的临床效用量身定制的VR干预措施.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 生物医学工程 生物医学工程
背景情况:
- 帕金森病 (PD) 显著损害了运动和非运动功能,降低了患者的生活质量.
- 传统的康复方法往往无法满足PD患者多样化的需求.
- 虚拟现实 (VR) 通过沉浸式和可定制的环境提供了一种创新的治疗方法.
研究的目的:
- 系统地审查和分析VR干预在帕金森病 (PD) 康复中的有效性.
- 将基于VR的康复与PD患者的传统疗法进行比较.
主要方法:
- 根据PRISMA指南,在五个数据库中进行了系统的文献搜索,直到2023年11月.
- 包括随机对照试验 (RCT),将VR干预与PD患者其他治疗方法进行比较.
- 提取的数据集中在运动和平衡结果上;使用RoB 2工具评估偏差风险.
主要成果:
- 对199名参与者进行的5项RCT的分析显示,VR显著改善了动态平衡,如Time Up-to-Go (TUG) 测试所示 (平均差异: -2.42,p=0.002).
- 然而,VR干预并没有显著改善静态平衡,伯格平衡量 (BBS) 偏好了对照组 (平均差异:3.28,p<0.00001).
结论:
- 在帕金森病 (PD) 患者中,VR干预显示出增强动态平衡和移动性的巨大潜力.
- 对静态平衡的影响有限,这表明需要定制VR康复策略.
- 解决成本,可访问性和标准化等挑战对于将VR纳入PD临床实践至关重要.
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