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Updated: Jan 17, 2026

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皮下尼沃卢马布的模型信息药物开发:使用临床试验模拟的药物动力学分析方法的比较

Yue Zhao1, Heather Vezina1, Zheyi Hu1

  • 1Bristol Myers Squibb, Princeton, New Jersey, USA.

CPT: pharmacometrics & systems pharmacology
|September 24, 2025
PubMed
概括

基于模型的药理动力学分析准确地确定了nivolumab在III期试验中的皮下和静脉注射配方的暴露. 这种基于模型的药物开发方法为评估药物疗效的传统方法提供了强大的替代方案.

关键词:
基于模型的药物开发.瘤学 在瘤学方面.药物动力学 药物动力学

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