相关实验视频

Updated: Jan 17, 2026

Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons
10:03

Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons

Published on: August 16, 2020

11.2K

缺少PINK1可导致利维体痴呆症的发展,同时存在Aβ病理

Tong-Yao Gao1,2, Xu-Zheng Wang3, Yu-Han Xie4

  • 1Department of Pharmacology, Zhejiang University School of Medicine, Hangzhou, China.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|September 24, 2025
PubMed
概括

由PTEN诱导的激酶1 (PINK1) 缺陷通过破坏α-synuclein酸化,加剧了Lewy体病理在患有Lewy体 (DLB) 的痴呆症中. 这项研究引入了一种用于DLB研究的新型小鼠模型.

关键词:
一个APP/PS1鼠标鼠标.阿尔茨海默病的疾病阿尔茨海默病的疾病.莱维的身体.利维神经炎是一种神经炎.在PTEN诱导的激酶1中.帕金森病的疾病.氨基βββββββββββββββββββββββββ患有利维体痴呆症的痴呆症酸化的方法是:光化.α-synuclein 是一种同核蛋白.

更多相关视频

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains09:27

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains

Published on: January 5, 2016

18.0K
Technique for Intranasal Administration of α-Synuclein Aggregates04:49

Technique for Intranasal Administration of α-Synuclein Aggregates

Published on: November 8, 2024

1.0K

相关概念视频

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
1.8K
Neural Regulation01:37

Neural Regulation

Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
43.1K
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.6K