经济上具有成本效益的生产媒介优化Bacillus subtilis Ö-4-68:水产养殖的潜在益生菌
Sezen Demirhan-Yazıcı1, Kemal Karaca1, Ayşe Nalbantsoy2
1Graduate School of Natural and Applied Sciences, Department of Bioengineering, Ege University, Izmir, Turkey.
Biotechnology progress
|September 24, 2025
概括
细菌益生菌通过改善鱼类健康和生长来增强水产养殖的可持续性. 细菌细菌Ö-4-68显示出优越的益生菌潜力,优化生产以实现成本效益的生物质产量.
科学领域:
- 水产养殖是水产养殖的一种方式.
- 微生物学 微生物学
- 动物科学动物科学
背景情况:
- 益生菌,特别是细菌物种,对于可持续的水产养殖至关重要,提供诸如改善肠道健康,免疫力和鱼类抗病原体等好处.
- 在水产养殖中使用细菌是一种提高生产率和减少对抗生素依赖的战略.
研究的目的:
- 评估Bacillus分离物对常见鱼类病原体的益生菌性质.
- 选抗生素耐药性,胃酸耐受性,以及其他功能特征有前途的Bacillus分离物.
- 使用响应表面方法 (RSM) 优化Bacillus subtilis Ö-4-68的生产介质,以获得高生物质产量.
主要方法:
- 使用交叉条纹和阿加井扩散试验对Aeromonas hydrophila,Vibrio anguillarum,Lactococcus garvieae和Yersinia ruckeri进行了抗菌活性评估.
- 评估了抗生素耐药性,胃汁耐受性,胆汁耐受性,酶活性 (蛋白酶,氨基酶,脂酶,细胞酶) 和生物膜形成.
- 用响应表面方法 (RSM) 来优化Bacillus subtilis Ö-4-68的生产媒介.
主要成果:
- 细菌分离物对鱼类病原体的抗菌活性得到证实.
- 细菌细菌 Ö-4-68 证明了最重要的益生菌特性.
- 确定了一种经济和成本效益的生产媒介,以实现Bacillus subtilis Ö-4-68的高生物质产量.
结论:
- 细菌细菌 Ö-4-68 是一个非常有前途的益生菌候选人,用于水产养殖.
- 优化的生产条件使得这种有益细菌的经济高效,大规模培养成为可能.
- 该研究支持使用Bacillus益生菌作为水产养殖中抗生素的可持续替代品.
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