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Updated: Jan 17, 2026

Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta
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环盒 E3 合酶 目标 N-终端 氨酸 55 调节 Sp7 蛋白的周转

Abeera Sikandar1, Hani Ali1, Anabia Javed1

  • 1Department of Oral and Maxillofacial Surgery, Institute of Oral Health Research, School of Dentistry, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Journal of cellular biochemistry
|September 24, 2025
PubMed
概括

特异性蛋白7 (Sp7) 是由Rbx1和Rbx2E3连接酶调节的,这些连接酶将其定位为ubiquitination和proteasomal降解. 失去Rbx2会增加骨质母细胞的分化和骨的形成.

关键词:
环盒 E3 连接酶Rbx1和Rbx2的细胞分布方式Sp7无处不在的存在骨质母细胞分化的区别.蛋白质降解 蛋白质降解

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