通过触发JAK/STAT通路,SNORA33促进清细胞细胞癌的发展和对苏尼提尼布的抗性

Jiajia Sun1, Shuo Zhao1, Xiaochen Ren1

  • 1Department of Urology, Qilu Hospital of Shandong University, Jinan, Shandong, China.

IUBMB life
|September 24, 2025
PubMed
概括

在清细胞细胞癌 (ccRCC) 中,SNORA33的高度表达,促进瘤的进展和抗苏尼替尼的耐药性. 这种小核RNA (snoRNA) 可能作为ccRCC免疫疗法预测的生物标志物.

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