与代谢功能障碍相关的脂肪性肝病患者的饮食模式和心血管死亡率之间的关联
Yu-Jin Kwon1, Hye Sun Lee2, Ji-Won Lee3,4
1Department of Family Medicine, Yonsei University College of Medicine, Yongin Severance Hospital, Yongin, Republic of Korea.
Endocrine
|September 24, 2025
概括
坚持韩国地中海式饮食显著降低了与代谢功能障碍相关的脂肪性肝病 (MASLD) 患者心血管疾病死亡风险. 这种饮食模式在这个患者群体中提供了管理心脏健康的保护策略.
科学领域:
- 心血管健康 心血管健康
- 代谢障碍 代谢障碍 代谢障碍
- 营养流行病学 营养流行病学
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 与心血管疾病 (CVD) 风险增加有关.
- 确定保护性饮食策略对于管理MASLD患者心血管疾病风险至关重要.
研究的目的:
- 为了检查饮食模式和CVD死亡率之间的关联,在一个韩国人口与MASLD.
- 为了确定特定的饮食模式是否可以减轻MASLD患者的心血管风险.
主要方法:
- 在韩国基因组和流行病学研究 (KoGES) (2004-2013) 中,对32,091名韩国成年人 (年龄≥40) 的基线数据进行分析.
- 通过食物频率问卷评估饮食摄入量;使用主要成分分析确定饮食模式.
- 考克斯比例危险模型用于评估心血管疾病死亡风险,以多个混因素进行调整.
主要成果:
- 坚持韩国地中海式饮食与MASLD患者心血管疾病死亡率的降低有显著关联.
- 韩国地中海式饮食的最高四分之一的个人,心血管疾病死亡率的风险降低了33% (HR:0.67,95%CI:0.45-1.00).
- 其他饮食模式 (加工食品,动物蛋白,谷物,精制碳水化合物/丰富脂肪) 与心血管疾病死亡率没有显著关联.
结论:
- 韩国地中海风格的饮食模式与韩国成人患有MASLD的心血管疾病死亡率较低有关.
- 这种饮食方法可以作为MASLD患者心血管风险管理的有效策略.
- 研究结果表明,韩国地中海风格饮食的好处延伸到患有MASLD的非西方人口.
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