相关实验视频
Updated: Jan 6, 2026

04:26
Postoperative Ileus Murine Model
Published on: July 12, 2024
1.2K
阿片类药物给药和减少儿科伊利奥科里克内接收
Karina Burke1, Itai Shavit2, Daniel M Cohen3
1Department of Pediatrics, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
JAMA network open
|September 24, 2025
概括
芬太尼在输入静脉受精前给药对儿童的降低并没有与降低失败有关. 这表明芬太尼在儿科内治疗期间的疼痛管理中是一种安全的选择.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 疼痛管理 疼痛管理
- 外科手术的结果
背景情况:
- 乳性肠是儿童肠道阻塞的常见原因,往往需要痛苦的减少程序.
- 由于担心潜在的胃肠道减速和未能减少的担忧,镇静和止痛药不被例行使用.
- 芬太尼的使用与儿科患者的失败的静脉吸收减少之间的关联尚未得到充分证实.
研究的目的:
- 为了研究芬太尼的管理和未能减少经历了小眼球内肠缩减少的儿童之间的联系.
- 评估芬太尼作为儿科内宫内的止痛选择的安全性和有效性.
主要方法:
- 一项涉及14个国家的86个儿科三级护理中心的横截面研究的二次分析.
- 包括3184名年龄在4-48个月的儿童,患有大脑内肠接和试图减少的情况.
- 分析了使用双变量和多变量分析的芬太尼使用,患者人口统计和减少结果的数据.
主要成果:
- 芬太尼在减肥前给了3.66%的患者.
- 总体而言,未能减排的总比率为15.20%.
- 在未经调整的 (OR,0.66) 和调整的分析中,芬太尼的使用没有与降低失败有关. 预先存在的胃肠道异常,减少的时间较长,年龄较小与减少的失败有关.
结论:
- 在试图减轻儿科大脑内肠塞的前,芬太尼的使用与减轻失败无关.
- 这些发现支持考虑芬太尼作为一种安全的治疗选择,用于管理与减少儿童肠道接相关的疼痛.
- 进一步的研究可能会探索在这个人群中使用芬太尼的最佳剂量和时间.
相关概念视频
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
593
Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
593
Inflammatory Bowel Disease V: Surgical Management
420
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
420
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
496
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
496
Drugs for Treatment of Constipation-Predominant IBS
664
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
664
Drugs for Treatment of Diarrhea-Predominant IBS
590
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
590
Inflammatory Bowel Disease IV: Pharmacological Management
427
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
427

